Both products are made from a combination of natural and synthetic ingredients and are no medications. They affect metabolic systems of the body, leading to peace and serenity (NEKTON-Keep-Cool) or support healthy joint function (NEKTON-Pro-Active). For example, the amino acid L-tryptophan (NEKTON-Keep-Cool) is converted to the neurotransmitter serotonin in the body. So (2- 4 weeks) with time increased the levels of serotonin and the animals are calm and relaxed. Even with NEKTON-Pro-Active ingredients, glucosamine, chondroitin and MSM are first metabolized to then accumulate in the joints and can lead to an improvement in joint function.